SLEEP DISTURBANCES
our therapeutic area

SLEEP

One of the most important life-maintaining functions is sleep. The body has only limited reserves of energy at its disposal and has to top these up when they have been exhausted. During sleep, breathing and pulse rates slow down and blood pressure and body temperature drop.
The events of the day are relived and processed, journeys are made through fantastic dream worlds, and the body and mind regenerate. Hence the overwhelming importance of healthy sleep.

Duration of sleep

For regeneration, every person needs a different amount of sleep. It is true, however, that people need less sleep as they grow older. Whereas a newborn baby sleeps for 18 hours a day on average, toddlers manage with approx. 12 hours and adolescents with 9 hours. Adults sleep on average for one third of the day. The need for sleep can fall to below 6 hours a day. People often also forget that they had an afternoon snooze and shouldn’t therefore be surprised if the subsequent night seems to be short.

SLEEP PHASES

Sleep research has made great progress in recent years. Nowadays, electroencephalography (EEG) is used to record brain activity and bodily functions and the interplay between them. 
And it has been observed that the depth of sleep is not the same during all phases. The cycle of sleep begins with the non-rapid eye movement (REM) phase. During this deep-sleep phase, body temperature and blood pressure fall, the eyes remain still, and no dreams occur. This gives way to the REM phase, so called because it is characterised by energetic eye movements.
During the REM phase, the EEG shows increased activity, dreaming is intense, and people easily wake up. Both phases alternate at regular intervals. Each ‘cycle’ lasts about 1.5 hours all told, although as the night progresses, the relative lengths of the two different phases shift so that the REM phase increases from 5 to up to 50 minutes as sleep progresses.


close close

SLEEP PHASES

Sleep research has made great progress in recent years. Nowadays, electroencephalography (EEG) is used to record brain activity and bodily functions and the interplay between them. 

 

 
Baldurat® – Active ingredient: dry extract of valerian root (3 - 6 : 1) [extraction agent: 70% ethanol (V/V)]. Indicated for the treatment of restlessness and disturbances in going sleep of nervous origin. For information on risks and side effects, read the package leaflet and ask your doctor or pharmacist. G. Pohl-Boskamp GmbH & Co. KG, D-25551 Hohenlockstedt, Germany (July 2001).

Nitrolingual akut® Spray – Active ingredient: glyceryl trinitrate. Composition: 1 metered dose oromucusal spray contains 0.4 mg glyceryl trinitrate. Other ingredients: medium-chain triglycerides and partial glycerides, ethanol anhydrans, peppermint oil. Indications: prophylaxis and treatment of acute attacks of angina pectoris, acute myocardial infarction, acute left-ventricular heart failure, catheter-induced coronary spasms. Contraindications: hypersensitivity to any of the ingredients or other nitrate compounds, acute circulatory failure, cardiogenic shock, marked hypotension (syst BP < 90 mmHg), intake of phosphodiesterase inhibitors for the treatment of erectile dysfunction or pulmonary arterial hypertension. Caution in cases of hypertrophic obstructive cardiomyopathy, constrictive pericarditis, pericardial tamponade, low filling pressures (e.g. in cases of acute MI; avoid syst BP < 90 mmHg), aortic and/or mitral stenosis, orthostatic circulatory disorders, increased intracranial pressure. During pregnancy and breast-feeding, only after careful consideration whether the benefits outweigh the risks. Side effects: headache very frequent at the start of treatment, frequent hypotension with reflex tachycardia, drowsiness, dizziness and weakness. Occasional nausea, vomiting, flush, allergic skin reactions, marked decreases in blood pressure with exacerbation of angina pectoris symptoms, bradycardia with fainting. Very rare, exfoliative dermatitis. Development of tolerance and cross tolerance possible, avoid continuous high dosing. Hypoxaemia and ischaemia may occur in CHD. The ability to drive vehicles or operate machines may be impaired, especially in combination with alcohol consumption. PO. G. Pohl-Boskamp GmbH & Co. KG, 25551 Hohenlockstedt, Germany (1).
GeloMyrtol® forte – Active ingredient: distillate of a mixture of rectified eucalyptus oil, rectified sweet orange oil, rectified myrtle oil and rectified lemon oil (66:32:1:1) (Myrtol® standardized). Indicated for acute and chronic bronchitis and inflammation of the maxillary sinuses (sinusitis). For information on risks and side effects, read the package leaflet and ask your doctor or pharmacist. G. Pohl-Boskamp GmbH & Co. KG, 25551 Hohenlockstedt, Germany (01/6).
Laxopol® 1.0 g – Active ingredient: refined castor oil. For the short-term treatment of constipation. Medical advice should sought for constipation that lasts for longer than 1 week. For information on risks and side effects, read the package leaflet and ask your doctor or pharmacist. G. Pohl-Boskamp GmbH & Co. KG, 25551 Hohenlockstedt, Germany (6).
GeloBronchial®-Saft – Active ingredient: liquid extract of thyme. Indications: common cold like disorders of the airways with catarrh, alleviation of symptoms of bronchitis. Warning: Ingredients include invert sugar syrup and 6.3 Vol.-% alcohol. Diabetics: sugar content of 0.75 BEU per 15 mL syrup. For information on risks and side effects, read the package leaflet and ask your doctor or pharmacist. G. Pohl-Boskamp GmbH & Co. KG, 25551 Hohenlockstedt, Germany (01/11).
GeloDurat®-Salbe – Active ingredient: eucalyptus oil and levomenthol. For external use to alleviate the symptoms of  respiratory tract infections (common cold, hoarseness and uncomplicated bronchial catarrh). For information on risks and side effects, read the package leaflet and ask your doctor or pharmacist. G. Pohl-Boskamp GmbH & Co. KG, 25551 Hohenlockstedt, Germany (01/5).

Nitrolingual® infus. – Active ingredient: glycerol trinitrate. Composition: 1 ml infusion solution contains 1 mg glycerol trinitrate. Other ingredients: glucose monohydrate (Ph.Eur.), 10% hydrochloric acid solution (for pH adjustment), water for injections. Indications: severe angina pectoris, acute myocardial infarction, acute left-ventricular heart failure, hypertensive crisis with acute heart failure, controlled hypotension. Contraindications: hypersensitivity to any of the ingredients or other nitrate compounds, acute circulatory failure, cardiogenic shock, toxic pulmonary oedema, marked hypotension (syst BP < 90 mmHg), disorders with increased intracranial pressure, intake of phosphodiesterase inhibitors for the treatment of erectile dysfunction or pulmonary arterial hypertension. Caution in cases of hypertrophic obstructive cardiomyopathy, constrictive pericarditis, pericardial tamponade, low filling pressures (e.g. in cases of acute MI; avoid syst BP < 90 mmHg), aortic and/or mitral valve stenosis, tendency to orthostatic circulatory disorders, severe liver or kidney disturbances. During pregnancy and breast-feeding, only if prescribed by a physician. Side effects: headache very frequent at the start of treatment; hypotension with reflex tachycardia may occur. Occasional nausea, vomiting, flush, allergic skin reactions, marked decreases in blood pressure with exacerbation of angina pectoris symptoms, bradycardia with fainting and synopses. Very rare, exfoliative dermatitis. Development of tolerance and cross tolerance possible, avoid continuous high dosing. Hypoxaemia and ischaemia may occur in CHD. The ability to drive vehicles or operate machines may be impaired, especially in combination with alcohol consumption. PO. G. Pohl-Boskamp GmbH & Co. KG, 25551 Hohenlockstedt, Germany (July 2008).
GeloVital® Lebertrankapseln – 0.5 g/1.0 g – Active ingredient: Codliveroil for general strengthening and invigoration. For information on risks and side effects, read the package leaflet and ask your doctor or pharmacist. G. Pohl-Boskamp GmbH & Co. KG, 25551 Hohenlockstedt, Germany (01/5/2).

GeloNasal®- 0.05%/-Spray 0.10% – Active ingredient: xylometazoline hydrochloride. Indications: for local application in  the nose. Contains the alpha-sympathomimetic xylometazoline. This substance narrows the blood vessels thereby reducing swelling of the mucous membrane. GeloNasal®-Tropfen 0.05%: for children between 2 and 6 years; GeloNasal®-Spray 0.10%: for schoolchildren older than 6 years and adults. For information on risks and side effects, read the package leaflet and ask your doctor or pharmacist. G. Pohl-Boskamp GmbH & Co. KG, 25551 Hohenlockstedt, Germany (01/13/13).
Gelo®-Bronchialtee 400 – Active ingredients: dry extract of thyme (6.0 – 10.0:1) [70% (V/V) ethanol] and ivy leaves (4.0 – 7.5:1) [30% (V/V) ethanol]. Indications: common cold and upper respiratory tract infections (catarrh), alleviation of symptoms of bronchitis. For information on risks and side effects, read the package leaflet and ask your doctor or pharmacist. G. Pohl-Boskamp GmbH & Co. KG, 25551 Hohenlockstedt (01/01).